Dr Vaclav Gergelits is currently a postdoctoral researcher at the Babraham Institute, Cambridge, where he joined the (neuro)immunology laboratory of Prof. Adrian Liston. Dr Gergelits holds degrees in General Mathematics (BSc), Mathematical Statistics (MSc), and Bioinformatics/Genetics (PhD, Charles University, Prague, Czech Republic).
He uses mathematical modelling and bioinformatics tools to understand the dynamics of immune cells and tissue residency of regulatory T cells (Tregs) in particular. Tregs are white blood cells controlling the activity of our immune system as well as participating in tissue repair and homeostasis. The findings about the expected dwell time and apoptosis rate of T cells in tissues can be also harnessed therapeutically.
In continuation, focussing on the brain, Dr Gergelits is aiming to understand the interactions of the immune system with brain-specific immunology in health and brain injury and their consequences for ageing. Here, he also benefits from utilising mouse genetics tools to map and model the fate of brain immune cells and their interacting partners and how these are perturbed under adverse conditions.